BDBM50002660 ((2S,3S)-2-Benzhydryl-1-aza-bicyclo[2.2.2]oct-3-yl)-benzyl-amine::(2-Benzhydryl-1-aza-bicyclo[2.2.2]oct-3-yl)-benzyl-amine::CHEMBL431690::L-703605

SMILES C(N[C@H]1C2CCN(CC2)[C@H]1C(c1ccccc1)c1ccccc1)c1ccccc1

InChI Key InChIKey=SVHVLAGNGAWUQU-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50002660   

TargetSubstance-P receptor(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50002660(CHEMBL431690 | L-703605 | (2-Benzhydryl-1-aza-bicy...)
Affinity DataIC50: 16nMAssay Description:Binding affinity towards Tachykinin receptor 1 in human IM-9 cells using [3H]-substance P as ligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSubstance-P receptor(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50002660(CHEMBL431690 | L-703605 | (2-Benzhydryl-1-aza-bicy...)
Affinity DataIC50: 0.0850nMAssay Description:Inhibition of binding of [125I]SP to the CHO cell line expressing human Tachykinin receptor 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSubstance-P receptor(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50002660(CHEMBL431690 | L-703605 | (2-Benzhydryl-1-aza-bicy...)
Affinity DataIC50: 110nMAssay Description:Binding potency against SP receptor in bovine caudate using [3H]- as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2010
Entry Details Article

TargetSubstance-P receptor(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50002660(CHEMBL431690 | L-703605 | (2-Benzhydryl-1-aza-bicy...)
Affinity DataIC50: 150nMAssay Description:Displacement of [125]Substance P Binding from human Neurokinin NK1 receptor in CHO CellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2010
Entry Details Article

TargetSubstance-P receptor(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50002660(CHEMBL431690 | L-703605 | (2-Benzhydryl-1-aza-bicy...)
Affinity DataIC50: 28.8nMAssay Description:Binding affinity was measured against the Tachykinin receptor 1 in CHO-expressed hNK1 using [125I]SP.More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2013
Entry Details Article
PubMed