BDBM50053548 4-Furan-3-yl-7-[3-(3-hydroxy-6,8-dioxa-bicyclo[3.2.1]oct-3-yl)-benzyloxy]-naphthalene-2-carbonitrile::CHEMBL97380::L-702-539

SMILES OC1(CC2COC(C1)O2)c1cccc(COc2ccc3c(cc(cc3c2)C#N)-c2ccoc2)c1

InChI Key

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50053548   

TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50053548(L-702-539 | 4-Furan-3-yl-7-[3-(3-hydroxy-6,8-dioxa...)
Affinity DataIC50: 190nMAssay Description:Potency to inhibit oxidation of arachidonic acid by recombinant human 5-lipoxygenaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2012
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50053548(L-702-539 | 4-Furan-3-yl-7-[3-(3-hydroxy-6,8-dioxa...)
Affinity DataIC50: 190nMAssay Description:Inhibition of oxidation of arachidonic acid by human 5-Lipoxygenase using spectrophotometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/4/2012
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50053548(L-702-539 | 4-Furan-3-yl-7-[3-(3-hydroxy-6,8-dioxa...)
Affinity DataIC50: 190nMAssay Description:Inhibition of human 5-LO expressed in Sf9 cells by spectrophotometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed