BDBM50049481 (R)-N-(1-((2'-(2H-tetrazol-5-yl)biphenyl-4-yl)methyl)-2-oxo-2,3,4,5-tetrahydro-1H-benzo[b]azepin-3-yl)-3-amino-3-methylbutanamide::3-Amino-3-methyl-N-{(R)-2-oxo-1-[2'-(1H-tetrazol-5-yl)-biphenyl-4-ylmethyl]-2,3,4,5-tetrahydro-1H-benzo[b]azepin-3-yl}-butyramide::3-Amino-3-methyl-N-{2-oxo-1-[2'-(1H-tetrazol-5-yl)-biphenyl-4-ylmethyl]-2,3,4,5-tetrahydro-1H-benzo[b]azepin-3-yl}-butyramide::3-Amino-3-methyl-N-{2-oxo-1-[2'-(2H-tetrazol-5-yl)-biphenyl-4-ylmethyl]-2,3,4,5-tetrahydro-1H-benzo[b]azepin-3-yl}-butyramide::Arg-Pro-Lys-Pro-Phe-Trp-Leu::CHEMBL308716::L-692429

SMILES CC(C)(N)CC(=O)N[C@@H]1CCc2ccccc2N(Cc2ccc(cc2)-c2ccccc2-c2nnn[nH]2)C1=O

InChI Key InChIKey=SBJLJOFPWOYATP-UHFFFAOYSA-N

Data  1 KI  4 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50049481   

TargetGrowth hormone secretagogue receptor type 1(Rat)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50049481(3-Amino-3-methyl-N-{2-oxo-1-[2'-(1H-tetrazol-5-yl)...)
Affinity DataEC50:  60nMAssay Description:In vitro growth hormone release was determined in rat pituitary cell assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGrowth hormone secretagogue receptor type 1(Rat)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50049481(3-Amino-3-methyl-N-{2-oxo-1-[2'-(1H-tetrazol-5-yl)...)
Affinity DataIC50: 60nMAssay Description:Inhibition against rat growth hormone secretagogue (GHS) receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGrowth hormone secretagogue receptor type 1(Pig)
Novo Nordisk

Curated by ChEMBL
LigandPNGBDBM50049481(3-Amino-3-methyl-N-{2-oxo-1-[2'-(1H-tetrazol-5-yl)...)
Affinity DataIC50: 63nMAssay Description:Inhibition against pig growth hormone secretagogue (GHS) receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetType-1 angiotensin II receptor(Human)
Novo Nordisk

Curated by ChEMBL
LigandPNGBDBM50049481(3-Amino-3-methyl-N-{2-oxo-1-[2'-(1H-tetrazol-5-yl)...)
Affinity DataIC50: 3.60E+3nMAssay Description:Inhibition against human angiotensin II receptor, type 1 (AG2-R)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGrowth hormone secretagogue receptor type 1(Human)
Novo Nordisk

Curated by ChEMBL
LigandPNGBDBM50049481(3-Amino-3-methyl-N-{2-oxo-1-[2'-(1H-tetrazol-5-yl)...)
Affinity DataIC50: 2.80E+3nMAssay Description:Inhibition against human growth hormone secretagogue (GHS) receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50049481(3-Amino-3-methyl-N-{2-oxo-1-[2'-(1H-tetrazol-5-yl)...)
Affinity DataEC50:  60nMAssay Description:Ability to release growth hormone in a rat pituitary cell assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2013
Entry Details Article

TargetGrowth hormone secretagogue receptor type 1(Human)
Novo Nordisk

Curated by ChEMBL
LigandPNGBDBM50049481(3-Amino-3-methyl-N-{2-oxo-1-[2'-(1H-tetrazol-5-yl)...)
Affinity DataKi:  63nMAssay Description:Binding Affinity against Growth hormone secretagogue receptor of swine using [35S]MK-0677 as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed