BDBM50366827 CHEMBL125181::L-371912

SMILES CN[C@H](Cc1ccccc1)C(=O)N2CCC[C@H]2C(=O)NCC3CCC(CC3)N

InChI Key InChIKey=MDSVGJAUFNXYRR-UHFFFAOYSA-N

Data  3 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50366827   

TargetProthrombin(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50366827(L-371912 | CHEMBL125181)
Affinity DataIC50: 6nMAssay Description:Inhibition of thrombin-catalyzed hydrolysis of a standard substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/9/2012
Entry Details Article
PubMed
TargetProthrombin(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50366827(L-371912 | CHEMBL125181)
Affinity DataKi:  4.90nMAssay Description:Binding affinity towards thrombin was determinedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/9/2012
Entry Details Article
PubMed
TargetProthrombin(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50366827(L-371912 | CHEMBL125181)
Affinity DataKi:  5nMAssay Description:Inhibitory activity against thrombin IIaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/8/2012
Entry Details Article
PubMed
TargetProthrombin(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50366827(L-371912 | CHEMBL125181)
Affinity DataKi:  5nMAssay Description:Binding affinity towards thrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/6/2012
Entry Details Article
PubMed