BDBM50407812 KW-2450::Kw-2450

SMILES Cc1ccc(cc1)S(O)(=O)=O.Cc1ccsc1C(=O)Nc1cc(CN2CCN(CC2)C(=O)CO)ccc1\C=C\c1n[nH]c2ccccc12

InChI Key InChIKey=SIJKXSMUXNJNQM-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50407812   

TargetAurora kinase A(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50407812(Kw-2450 | KW-2450)
Affinity DataIC50: 215nMAssay Description:Inhibition of human Aurora A kinase expressed in MDA-MB-468 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetAurora kinase B(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50407812(Kw-2450 | KW-2450)
Affinity DataIC50: 478nMAssay Description:Inhibition of human Aurora B kinase expressed in MDA-MB-468 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetAurora kinase B(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50407812(Kw-2450 | KW-2450)
Affinity DataIC50: 272nMAssay Description:Inhibition of human Aurora B kinase expressed in SUM149 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetAurora kinase B(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50407812(Kw-2450 | KW-2450)
Affinity DataIC50: 66nMAssay Description:Inhibition of human Aurora B kinase expressed in MDA-MB-231 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetInsulin-like growth factor 1 receptor(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50407812(Kw-2450 | KW-2450)
Affinity DataIC50: 2nMAssay Description:Inhibition of human IGF1R expressed in MDA-MB-468 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetInsulin-like growth factor 1 receptor(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50407812(Kw-2450 | KW-2450)
Affinity DataIC50: 2nMAssay Description:Inhibition of human IGF1R expressed in SUM149 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed