BDBM50375642 CHEMBL406381::KRN-633

SMILES CCCNC(=O)Nc1ccc(Oc2ncnc3cc(OC)c(OC)cc23)cc1Cl

InChI Key InChIKey=VPBYZLCHOKSGRX-UHFFFAOYSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50375642   

TargetVascular endothelial growth factor receptor 1(Human)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50375642(KRN-633 | CHEMBL406381)
Affinity DataIC50: 170nMAssay Description:Inhibition of VEGFR1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 1(Human)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50375642(KRN-633 | CHEMBL406381)
Affinity DataIC50: 1nMAssay Description:Inhibition of human VEGFR1 in HUVEC cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50375642(KRN-633 | CHEMBL406381)
Affinity DataIC50: 160nMAssay Description:Inhibition of VEGFR2More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 3(Human)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50375642(KRN-633 | CHEMBL406381)
Affinity DataIC50: 125nMAssay Description:Inhibition of VEGFR3More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetPlatelet-derived growth factor receptor alpha(Human)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50375642(KRN-633 | CHEMBL406381)
Affinity DataIC50: 970nMAssay Description:Inhibition of PDGFRalphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetMast/stem cell growth factor receptor Kit(Human)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50375642(KRN-633 | CHEMBL406381)
Affinity DataIC50: 4.33E+3nMAssay Description:Inhibition of c-kitMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50375642(KRN-633 | CHEMBL406381)
Affinity DataIC50: 1nMAssay Description:Inhibition of human VEGFR2 in HUVEC cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed