BDBM50478922 CHEMBL447735::KNI-10680

SMILES CC(C)(C)CNC(=O)[C@H]1N(CSC1(C)C)C(=O)[C@@H](O)[C@H](Cc1ccccc1)NC(=O)[C@@H](NC(=O)[C@@H](N)c1ccccc1)C(C)(C)C

InChI Key InChIKey=PITLJSCJQDTWGC-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50478922   

TargetProtease(Human T-cell leukemia virus type I)
Kyoto Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50478922(KNI-10680 | CHEMBL447735)
Affinity DataIC50: 37nMAssay Description:Inhibition of HTLV-1 recombinant protease L40I mutantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2020
Entry Details Article
PubMed
TargetProtease(Human T-cell leukemia virus type I)
Kyoto Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50478922(KNI-10680 | CHEMBL447735)
Affinity DataIC50: 180nMAssay Description:Inhibition of HTLV1 protease L40I mutantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2020
Entry Details Article
PubMed
TargetProtease(Human T-cell leukemia virus type I)
Kyoto Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50478922(KNI-10680 | CHEMBL447735)
Affinity DataIC50: 37nMAssay Description:Inhibition of HTLV-1 protease L40I mutant by fluorimetric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2020
Entry Details Article
PubMed