BDBM50414348 CHEMBL540946::KN-04

SMILES CN(C(CN1CCN(CC1)c1ccccc1)Cc1ccc(OS(=O)(=O)c2cccc3cnccc23)cc1)S(=O)(=O)c1cccc2cnccc12

InChI Key InChIKey=ICKAEBJBMGMPQE-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50414348   

TargetP2X purinoceptor 7(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50414348(KN-04 | CHEMBL540946)
Affinity DataIC50: 15.8nMAssay Description:Antagonist activity at P2X7 receptor in human lymphocytes assessed as inhibition of ATP-induced Ba2+ influxMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed