BDBM223318 KDOAM-28

SMILES CCNC(=O)c1ccnc(CNCC(=O)N(CC)CCN(C)C)c1

InChI Key InChIKey=WXFDDWMINUVYFL-UHFFFAOYSA-N

Data  10 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 223318   

TargetLysine-specific demethylase 5B(Human)
University of Oxford

LigandPNGBDBM223318(KDOAM-28)
Affinity DataIC50: 98nMAssay Description:We previously described 4-carboxy-2-triazolopyridines as selective KDM2 inhibitors (England et al., 2014). In efforts to find alternative scaffolds b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/27/2017
Entry Details Article
PubMed
TargetLysine-specific demethylase 5A(Human)
University of Oxford

LigandPNGBDBM223318(KDOAM-28)
Affinity DataIC50: 300nMAssay Description:We previously described 4-carboxy-2-triazolopyridines as selective KDM2 inhibitors (England et al., 2014). In efforts to find alternative scaffolds b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/27/2017
Entry Details Article
PubMed
TargetLysine-specific demethylase 5B(Human)
University of Oxford

LigandPNGBDBM223318(KDOAM-28)
Affinity DataIC50: 100nMAssay Description:We previously described 4-carboxy-2-triazolopyridines as selective KDM2 inhibitors (England et al., 2014). In efforts to find alternative scaffolds b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/27/2017
Entry Details Article
PubMed
TargetLysine-specific demethylase 5C(Human)
University of Oxford

LigandPNGBDBM223318(KDOAM-28)
Affinity DataIC50: 200nMAssay Description:We previously described 4-carboxy-2-triazolopyridines as selective KDM2 inhibitors (England et al., 2014). In efforts to find alternative scaffolds b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/27/2017
Entry Details Article
PubMed
TargetLysine-specific demethylase 5D(Human)
University of Oxford

LigandPNGBDBM223318(KDOAM-28)
Affinity DataIC50: 200nMAssay Description:We previously described 4-carboxy-2-triazolopyridines as selective KDM2 inhibitors (England et al., 2014). In efforts to find alternative scaffolds b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/27/2017
Entry Details Article
PubMed
TargetLysine-specific demethylase 6B(Human)
University of Oxford

LigandPNGBDBM223318(KDOAM-28)
Affinity DataIC50: 8.00E+3nMAssay Description:We previously described 4-carboxy-2-triazolopyridines as selective KDM2 inhibitors (England et al., 2014). In efforts to find alternative scaffolds b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/27/2017
Entry Details Article
PubMed
TargetLysine-specific demethylase 5A(Human)
University of Oxford

LigandPNGBDBM223318(KDOAM-28)
Affinity DataIC50: 6.60E+3nMAssay Description:Inhibition of KDM5A (unknown origin ) by Alphascreen assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
TargetLysine-specific demethylase 5B(Human)
University of Oxford

LigandPNGBDBM223318(KDOAM-28)
Affinity DataIC50: 7.00E+3nMAssay Description:Inhibition of KDM5B (unknown origin ) by Alphascreen assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
TargetLysine-specific demethylase 5C(Human)
University of Oxford

LigandPNGBDBM223318(KDOAM-28)
Affinity DataIC50: 6.80E+3nMAssay Description:Inhibition of KDM5C (unknown origin ) by Alphascreen assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
TargetLysine-specific demethylase 5B(Human)
University of Oxford

LigandPNGBDBM223318(KDOAM-28)
Affinity DataIC50: 98nMAssay Description:Inhibition of KDM5B (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed