BDBM50371393 2,2,2-triphenylacetic acid::CHEMBL271207::J-640276::Triphenylacetic Acid

SMILES OC(=O)C(c1ccccc1)(c1ccccc1)c1ccccc1

InChI Key InChIKey=DCYGAPKNVCQNOE-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50371393   

LigandPNGBDBM50371393(CHEMBL271207 | Triphenylacetic Acid | 2,2,2-triphe...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of Gardos channel in human RBC assessed as inhibition of ionomycin-stimulated [86Rb] effluxMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2012
Entry Details Article
PubMed
TargetNuclear receptor subfamily 4 group A member 1(Human)
Ludwig Maximilian University of Munich

Curated by ChEMBL
LigandPNGBDBM50371393(CHEMBL271207 | Triphenylacetic Acid | 2,2,2-triphe...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inverse agonist activity at human Nur77 LBD transiently transfected in HEK293T cells incubated for 16 hrs by Gal4-hybrid reporter gene based Dual-glo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetNuclear receptor subfamily 4 group A member 2(Human)
Ludwig Maximilian University of Munich

Curated by ChEMBL
LigandPNGBDBM50371393(CHEMBL271207 | Triphenylacetic Acid | 2,2,2-triphe...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inverse agonist activity at human Nurr1 LBD transiently transfected in HEK293T cells incubated for 16 hrs by Gal4-hybrid reporter gene based Dual-glo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetNuclear receptor subfamily 4 group A member 3(Human)
Ludwig Maximilian University of Munich

Curated by ChEMBL
LigandPNGBDBM50371393(CHEMBL271207 | Triphenylacetic Acid | 2,2,2-triphe...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inverse agonist activity at human NOR-1 LBD transiently transfected in HEK293T cells incubated for 16 hrs by Gal4-hybrid reporter gene based Dual-glo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed