BDBM50564768 Azaepothilone b::BMS 247550-01::BMS-247550::BMS-247550-01::CHEBI:63605::Ixabepilone::Ixempra::Ixempra kit::NSC-747973

SMILES Cc1nc(cs1)/C=C(\C)/[C@@H]2C[C@H]3[C@](O3)(CCC[C@@H]([C@@H]([C@H](C(=O)C([C@H](CC(=O)N2)O)(C)C)C)O)C)C

InChI Key InChIKey=FABUFPQFXZVHFB-UHFFFAOYSA-N

Data  1 Kd

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50564768   

TargetApoptosis regulator Bcl-2(Human)
Central South University

Curated by ChEMBL
LigandPNGBDBM50564768(CHEBI:63605 | Ixabepilone | Azaepothilone b | Ixem...)
Affinity DataKd:  337nMAssay Description:Binding affinity to human recombinant Bcl-2 expressed in Escherichia coli by Surface plasmon resonance assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed