BDBM50158615 Ischemin

SMILES Cc1cc(c(cc1/N=N/c2cc(c(cc2N)O)C)S(=O)(=O)O)C

InChI Key InChIKey=UUECJWRVDTUDCB-UHFFFAOYSA-N

Data  2 KI  2 Kd

PDB links: 1 PDB ID matches this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50158615   

TargetCREB-binding protein(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50158615(Ischemin)
Affinity DataKd:  1.96E+4nMAssay Description:Binding affinity to CBP bromodomain (unknown origin) by fluorescence spectroscopic analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2017
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetCREB-binding protein(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50158615(Ischemin)
Affinity DataKd:  1.90E+4nMAssay Description:Binding affinity to CBP bromodomain (unknown origin) assessed as dissociation constant by tryptophan fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetBromodomain-containing protein 4(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50158615(Ischemin)
Affinity DataKi:  1.09E+4nMAssay Description:Inhibition of BRD4 BD1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetBromodomain-containing protein 4(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50158615(Ischemin)
Affinity DataKi:  1.97E+4nMAssay Description:Inhibition of BRD4 BD2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed