BDBM50027363 CHEBI:78420::Icariin

SMILES [#6]-[#8]-c1ccc(cc1)-c1oc2c(-[#6]\[#6]=[#6](\[#6])-[#6])c(-[#8]-[#6@@H]-3-[#8]-[#6@H](-[#6]-[#8])-[#6@@H](-[#8])-[#6@H](-[#8])-[#6@H]-3-[#8])cc(-[#8])c2c(=O)c1-[#8]-[#6@@H]-1-[#8]-[#6@@H](-[#6])-[#6@H](-[#8])-[#6@@H](-[#8])-[#6@H]-1-[#8]

InChI Key InChIKey=FOWGHWPWBKNRMX-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50027363   

TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
University of Milan

Curated by ChEMBL
LigandPNGBDBM50027363(CHEBI:78420 | Icariin)
Affinity DataIC50: 5.90E+3nMAssay Description:Inhibition of human recombinant PDE5A1 expressed in COS7 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2012
Entry Details Article
PubMed
TargetLysine-specific histone demethylase 1A(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50027363(CHEBI:78420 | Icariin)
Affinity DataIC50: 2.64E+4nMAssay Description:Inhibition of LSD1 (unknown origin) by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed