BDBM50590368 IY5511::RADOTINIB::Radotinib

SMILES Cc1cn(cn1)-c1cc(NC(=O)c2ccc(C)c(Nc3nccc(n3)-c3cnccn3)c2)cc(c1)C(F)(F)F

InChI Key InChIKey=DUPWHXBITIZIKZ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50590368   

TargetBreakpoint cluster region protein/Tyrosine-protein kinase ABL1(Human)
Hangzhou Medical College

Curated by ChEMBL
LigandPNGBDBM50590368(Radotinib | IY5511 | RADOTINIB)
Affinity DataIC50: 1.20nMAssay Description:Inhibition of BCR-ABL (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
PubMed