BDBM50628590 ISUZINAXIB

SMILES CCCc1c(O)n(nc1-c1ccccc1)-c1ccccn1

InChI Key InChIKey=LQKQLKMTJOMCMJ-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50628590   

TargetCytochrome b-245 heavy chain(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50628590(ISUZINAXIB)
Affinity DataKi:  570nMAssay Description:Binding affinity to human NOX2 assessed as reduction in ROS production using lucigenin as substrate in presence of NADPH by chemiluminescence base as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetNADPH oxidase 4(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50628590(ISUZINAXIB)
Affinity DataKi:  630nMAssay Description:Binding affinity to human NOX4 assessed as reduction in ROS production using lucigenin as substrate in presence of NADPH by chemiluminescence base as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetNADPH oxidase 1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50628590(ISUZINAXIB)
Affinity DataKi:  1.08E+3nMAssay Description:Binding affinity to human NOX1 assessed as reduction in ROS production using lucigenin as substrate in presence of NADPH by chemiluminescence base as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed