BDBM11319 (5-oxo-5,6-dihydroindolo[1,2-a]quinazolin-7-yl)acetic acid::2-{8-oxo-1,9-diazatetracyclo[8.7.0.0^{2,7}.0^{12,17}]heptadeca-2(7),3,5,10,12(17),13,15-heptaen-11-yl}acetic acid::CGP029482::CHEMBL92361::IQA

SMILES c1ccc2c(c1)c(c3n2-c4ccccc4C(=O)N3)CC(=O)O

InChI Key InChIKey=INSBKYCYLCEBOD-UHFFFAOYSA-N

Data  2 KI  3 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 11319   

TargetCasein kinase II subunit alpha(Human)
Osaka Prefecture University

Curated by ChEMBL
LigandPNGBDBM11319(IQA | 2-{8-oxo-1,9-diazatetracyclo[8.7.0.0^{2,7}.0...)
Affinity DataIC50: 390nMAssay Description:Inhibition of GST-fused human recombinant CK2alpha expressed in Escherichia coli HMS174 (DE3)More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCasein kinase II subunit alpha 3(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM11319(IQA | 2-{8-oxo-1,9-diazatetracyclo[8.7.0.0^{2,7}.0...)
Affinity DataIC50: 390nMAssay Description:Inhibition of CK2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetCasein kinase II subunit alpha(Human)
Osaka Prefecture University

Curated by ChEMBL
LigandPNGBDBM11319(IQA | 2-{8-oxo-1,9-diazatetracyclo[8.7.0.0^{2,7}.0...)
Affinity DataKi:  170nM ΔG°:  -9.14kcal/mole IC50: 390nMpH: 7.5 T: 2°CAssay Description:In vitro kinase assay using purified enzyme, was incubated at room temperature with substrate, and test compounds in the presence of 100 uM ATP/ [gam...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2006
Entry Details Article
PubMed
TargetCasein kinase II subunit alpha 3(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM11319(IQA | 2-{8-oxo-1,9-diazatetracyclo[8.7.0.0^{2,7}.0...)
Affinity DataKi:  170nMAssay Description:Binding affinity to CK2 (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed