BDBM205003 I-100

SMILES C[C@H]1OC(N)=N[C@@](CF)([C@H]1CF)c1cc(NC(=O)c2ccc(cn2)C#N)ccc1F

InChI Key InChIKey=BQBBOJMULMDYEB-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 205003   

TargetBeta-secretase 1(Human)
Shionogi

US Patent
LigandPNGBDBM205003(I-100)
Affinity DataIC50: 113nMpH: 5.0 T: 2°CAssay Description:48.5 μL of substrate peptide solution (Biotin-XSEVNLDAEFRHDSGC-Eu: X=ε-amino-n-capronic acid, Eu=Europium cryptate) was added to each well...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/7/2018
Entry Details
Go to US Patent