BDBM50206060 1-(2,5-dimethoxyphenethyl)-3-(5-bromopyridin-2-yl)thiourea::1-(5-Bromo-pyridin-2-yl)-3-[2-(2,5-dimethoxy-phenyl)-ethyl]-thiourea::1-(5-bromopyridin-2-yl)-3-(2,5-dimethoxyphenethyl)thiourea::CHEMBL240416::HI-236

SMILES COc1ccc(OC)c(CCNC(=S)Nc2ccc(Br)cn2)c1

InChI Key InChIKey=GNLVRKKIIIVZHZ-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50206060   

TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Institute

Curated by ChEMBL
LigandPNGBDBM50206060(1-(5-Bromo-pyridin-2-yl)-3-[2-(2,5-dimethoxy-pheny...)
Affinity DataIC50: 100nMAssay Description:Inhibition of recombinant HIV-1 reverse transcriptaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Institute

Curated by ChEMBL
LigandPNGBDBM50206060(1-(5-Bromo-pyridin-2-yl)-3-[2-(2,5-dimethoxy-pheny...)
Affinity DataIC50: 100nMAssay Description:Inhibition of purified recombinant HIV-1 reverse transcriptaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/29/2012
Entry Details Article
PubMed
TargetReverse transcriptase(Human immunodeficiency virus type 1)
University of Cape Town

Curated by ChEMBL
LigandPNGBDBM50206060(1-(5-Bromo-pyridin-2-yl)-3-[2-(2,5-dimethoxy-pheny...)
Affinity DataIC50: 38nMAssay Description:Inhibition of HIV1 reverse transcriptase-mediated thymidine incorporation into D23/D36 primer-template preincubated for 15 mins by polyacrylamide gel...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2020
Entry Details Article
PubMed
TargetReverse transcriptase(Human immunodeficiency virus type 1)
University of Cape Town

Curated by ChEMBL
LigandPNGBDBM50206060(1-(5-Bromo-pyridin-2-yl)-3-[2-(2,5-dimethoxy-pheny...)
Affinity DataIC50: 28nMAssay Description:Inhibition of HIV1 3B reverse transcriptaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2020
Entry Details Article
PubMed