BDBM50024447 (6E,8Z,11Z,14Z)-5-Hydroxy-icosa-6,8,11,14-tetraenoic acid::5-Hydroxy-icosa-6,8,11,14-tetraenoic acid::CHEMBL17695::HETE-(+/-)5::HETE-5(S)

SMILES CCCCC\C=C/C\C=C/C\C=C/C=C/C(O)CCCC(O)=O

InChI Key InChIKey=KGIJOOYOSFUGPC-UHFFFAOYSA-N

Data  4 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50024447   

LigandPNGBDBM50024447(HETE-5(S) | (6E,8Z,11Z,14Z)-5-Hydroxy-icosa-6,8,11...)
Affinity DataIC50: 7.70E+4nMAssay Description:Inhibition of rat basophilic leukemia-1 (RBL-1) 5-lipoxygenaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2012
Entry Details Article
PubMed
LigandPNGBDBM50024447(HETE-5(S) | (6E,8Z,11Z,14Z)-5-Hydroxy-icosa-6,8,11...)
Affinity DataIC50: 7.70E+4nMAssay Description:In vitro inhibitory activity against 5-lipoxygenase from rat basophilic leukemia cells.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2012
Entry Details Article
PubMed
TargetLeukotriene B4 receptor 1(Human)
Schering-Plough Research Institute

Curated by PDSP Ki Database
LigandPNGBDBM50024447(HETE-5(S) | (6E,8Z,11Z,14Z)-5-Hydroxy-icosa-6,8,11...)
Affinity DataKi:  1.00E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2012
Entry Details Article
PubMed
TargetLeukotriene B4 receptor 2(Human)
Schering-Plough Research Institute

Curated by PDSP Ki Database
LigandPNGBDBM50024447(HETE-5(S) | (6E,8Z,11Z,14Z)-5-Hydroxy-icosa-6,8,11...)
Affinity DataKi:  1.00E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2012
Entry Details Article
PubMed
TargetLeukotriene B4 receptor 2(Human)
Schering-Plough Research Institute

Curated by PDSP Ki Database
LigandPNGBDBM50024447(HETE-5(S) | (6E,8Z,11Z,14Z)-5-Hydroxy-icosa-6,8,11...)
Affinity DataKi:  3.00E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2012
Entry Details Article
PubMed
TargetLeukotriene B4 receptor 1(Human)
Schering-Plough Research Institute

Curated by PDSP Ki Database
LigandPNGBDBM50024447(HETE-5(S) | (6E,8Z,11Z,14Z)-5-Hydroxy-icosa-6,8,11...)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2012
Entry Details Article
PubMed