BDBM50102260 2-(2-Amino-4-carboxy-butyrylamino)-pentanedioic acid::CHEMBL318315::Glu(Glu)::Glu-Glu

SMILES N[C@@H](CCC(O)=O)C(=O)N[C@@H](CCC(O)=O)C(O)=O

InChI Key InChIKey=KOSRFJWDECSPRO-UHFFFAOYSA-N

Data  2 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50102260   

TargetGlutamate carboxypeptidase 2(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50102260(Glu-Glu | 2-(2-Amino-4-carboxy-butyrylamino)-penta...)
Affinity DataIC50: 750nMAssay Description:Inhibitory activity against expressed rat Glutamate carboxypeptidase II, using a substrate concentration of 5 uMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSolute carrier family 15 member 1(Human)
Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50102260(Glu-Glu | 2-(2-Amino-4-carboxy-butyrylamino)-penta...)
Affinity DataIC50: 6.20E+5nMAssay Description:Binding affinity to human PEPT1 assessed as inhibition of [14C]Gly-Sar uptake in MDCK cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2012
Entry Details Article
PubMed
TargetSolute carrier family 15 member 1(Human)
Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50102260(Glu-Glu | 2-(2-Amino-4-carboxy-butyrylamino)-penta...)
Affinity DataEC50:  1.00E+6nMAssay Description:Activation of human PEPT1 expressed in MDCK cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2012
Entry Details Article
PubMed