BDBM50422960 CHEMBL231184::GW855454X

SMILES Cc1ccc(-c2cc(Cl)ccc2OCc2ccc(F)cc2)n1-c1ccc(C)c(c1)C(O)=O

InChI Key InChIKey=YNGYDYOYWOAUDY-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50422960   

TargetThromboxane A2 receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50422960(GW855454X | CHEMBL231184)
Affinity DataIC50: 40nMAssay Description:Inhibition of human recombinant TP receptor expressed in CHO cells by calcium mobilisation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2013
Entry Details Article
PubMed
TargetProstaglandin E2 receptor EP1 subtype(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50422960(GW855454X | CHEMBL231184)
Affinity DataIC50: 5nMAssay Description:Displacement of [3H]PGE2 from human recombinant EP1 receptor expressed in CHOK1 cell membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2013
Entry Details Article
PubMed
TargetProstaglandin E2 receptor EP4 subtype(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50422960(GW855454X | CHEMBL231184)
Affinity DataIC50: 1.58E+4nMAssay Description:Binding affinity to human EP4 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2013
Entry Details Article
PubMed