BDBM50010475 GAVESTINEL::GV-150526X

SMILES OC(=O)c1[nH]c2cc(Cl)cc(Cl)c2c1\C=C\C(=O)Nc1ccccc1

InChI Key InChIKey=WZBNEZWCNKUOSM-UHFFFAOYSA-N

Data  2 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50010475   

TargetBile salt export pump(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50010475(GV-150526X | GAVESTINEL)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human BSEP expressed in baculovirus transfected fall armyworm Sf21 cell membranes vesicles assessed as reduction in ATP-dependent [3H]-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2019
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 1(Rat)
Glaxowellcome

Curated by ChEMBL
LigandPNGBDBM50010475(GV-150526X | GAVESTINEL)
Affinity DataKi:  8.5nMAssay Description:In vitro affinity of compound for the glycinergic site associated with NMDA receptor was assessed by inhibition of the binding of [3H]glycineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/7/2018
Entry Details Article
PubMed
TargetUracil nucleotide/cysteinyl leukotriene receptor(Human)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50010475(GV-150526X | GAVESTINEL)
Affinity DataKi:  1.63E+3nMAssay Description:Displacement of [3H]PSB-12150 from human GPR17 expressed in CHO-K1 cell membranes after 60 mins by heterologous competition binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2015
Entry Details Article
PubMed