BDBM50483144 CHEMBL1630057::GSK2210875

SMILES C[C@@H](OC(=O)Nc1ccccc1)c1sc2ncnn2c1C

InChI Key InChIKey=AOUUMBPBMVOBSP-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50483144   

TargetMetabotropic glutamate receptor 5(Human)
Medicines Research Centre

Curated by ChEMBL
LigandPNGBDBM50483144(GSK2210875 | CHEMBL1630057)
Affinity DataIC50: 3.16E+4nMAssay Description:Antagonist activity at mGluR5More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2020
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Human)
Medicines Research Centre

Curated by ChEMBL
LigandPNGBDBM50483144(GSK2210875 | CHEMBL1630057)
Affinity DataIC50: 40nMAssay Description:Antagonist activity at human mGluR5 expressed in CHO cells assessed as doxycycline induced calcium mobilizationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2020
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Mouse)
Medicines Research Centre

Curated by ChEMBL
LigandPNGBDBM50483144(GSK2210875 | CHEMBL1630057)
Affinity DataIC50: 32nMAssay Description:Antagonist activity at mGluR5 in mouse astrocytes assessed as inhibition of L-quisqualate induced calcium release by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2020
Entry Details Article
PubMed