BDBM50461671 GS-333126::GS-9190::Tegobuvir

SMILES Fc1ccccc1-c1nc2ccn(Cc3ccc(nn3)-c3ccc(cc3C(F)(F)F)C(F)(F)F)cc2n1

InChI Key InChIKey=XBEQSQDCBSKCHJ-UHFFFAOYSA-N

Data  2 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50461671   

TargetPotassium voltage-gated channel subfamily H member 2(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50461671(GS-333126 | GS-9190 | Tegobuvir)
Affinity DataIC50: 794nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50461671(GS-333126 | GS-9190 | Tegobuvir)
Affinity DataEC50:  2.90nMAssay Description:Inhibition of Hepatitis C virus genotype 1b NS5B RNA-dependent-RNA polymerase assessed as reduction in viral replication after 72 hrs by indirect imm...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50461671(GS-333126 | GS-9190 | Tegobuvir)
Affinity DataEC50:  2.90nMAssay Description:Inhibition of Hepatitis C virus genotype 1b NS5B RNA-dependent-RNA polymeraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50461671(GS-333126 | GS-9190 | Tegobuvir)
Affinity DataIC50: 794nMAssay Description:Inhibition of human ERG expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMed