BDBM50283049 (Z)-7-[(1R,2R,3S,5S)-5-(Biphenyl-4-ylmethoxy)-3-hydroxy-2-piperidin-1-yl-cyclopentyl]-hept-4-enoic acid::CHEMBL65030::GR 32191::GR-32191

SMILES O[C@H]1C[C@H](OCc2ccc(cc2)-c2ccccc2)[C@H](CC\C=C/CCC(O)=O)[C@H]1N1CCCCC1

InChI Key InChIKey=GQGRDYWMOPRROR-UHFFFAOYSA-N

Data  2 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50283049   

TargetThromboxane A2 receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50283049(GR 32191 | CHEMBL65030 | GR-32191 | (Z)-7-[(1R,2R,...)
Affinity DataIC50: 12nMAssay Description:In vitro thromboxane receptor antagonist activity was determined by inhibition of U-46619 induced aggregation of washed human plateletsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2010
Entry Details Article

TargetThromboxane A2 receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50283049(GR 32191 | CHEMBL65030 | GR-32191 | (Z)-7-[(1R,2R,...)
Affinity DataKi:  7.80nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2012
Entry Details Article
PubMed
TargetThromboxane-A synthase(Mouse)
Kyoto University

Curated by PDSP Ki Database
LigandPNGBDBM50283049(GR 32191 | CHEMBL65030 | GR-32191 | (Z)-7-[(1R,2R,...)
Affinity DataKi:  12nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/1/2012
Entry Details Article
PubMed