BDBM50406805 CHEMBL585793::GNF-Pf-4574

SMILES OC(CN1CCN(Cc2ccccc2)CC1)Cn1c2ccc(Cl)cc2c2cc(Cl)ccc12

InChI Key InChIKey=DDJRRLCZCHXFJP-UHFFFAOYSA-N

Data  2 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50406805   

TargetHeat shock protein 90, putative(Plasmodium falciparum (isolate 3D7))
Universidad De Navarra

Curated by ChEMBL
LigandPNGBDBM50406805(CHEMBL585793 | GNF-Pf-4574)
Affinity DataKd:  27nMAssay Description:Binding affinity to Plasmodium falciparum HSP90 nucleotide binding domain by SPR analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetHeat shock protein 90, putative(Plasmodium falciparum (isolate 3D7))
Universidad De Navarra

Curated by ChEMBL
LigandPNGBDBM50406805(CHEMBL585793 | GNF-Pf-4574)
Affinity DataKd:  2.81E+4nMAssay Description:Binding affinity to recombinant Plasmodium falciparum Hsp90 expressed in Escherichia coli BL21(DE3) pLysS by microscale thermophoresis assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed