BDBM50304834 CHEMBL578928::GNF-Pf-2094::N2-benzyl-N4-cyclohexyl-6-methylpyrimidine-2,4-diamine

SMILES Cc1cc(NC2CCCCC2)nc(NCc2ccccc2)n1

InChI Key InChIKey=GDKCAAWSNQLXNX-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50304834   

TargetCytochrome P450 3A4(Human)
Institute Infectious Diseases Initiative

Curated by ChEMBL
LigandPNGBDBM50304834(N2-benzyl-N4-cyclohexyl-6-methylpyrimidine-2,4-dia...)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of human CYP3A4More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetCytochrome P450 2C9(Human)
Institute Infectious Diseases Initiative

Curated by ChEMBL
LigandPNGBDBM50304834(N2-benzyl-N4-cyclohexyl-6-methylpyrimidine-2,4-dia...)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of human CYP2C9More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetCytochrome P450 2C19(Human)
Institute Infectious Diseases Initiative

Curated by ChEMBL
LigandPNGBDBM50304834(N2-benzyl-N4-cyclohexyl-6-methylpyrimidine-2,4-dia...)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of human CYP2C19More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetCytochrome P450 1A2(Human)
Institute Infectious Diseases Initiative

Curated by ChEMBL
LigandPNGBDBM50304834(N2-benzyl-N4-cyclohexyl-6-methylpyrimidine-2,4-dia...)
Affinity DataIC50: 3.10E+3nMAssay Description:Inhibition of human CYP1A2More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Institute Infectious Diseases Initiative

Curated by ChEMBL
LigandPNGBDBM50304834(N2-benzyl-N4-cyclohexyl-6-methylpyrimidine-2,4-dia...)
Affinity DataIC50: 4.20E+3nMAssay Description:Inhibition of human CYP2D6More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed