BDBM50368092 GNF-PF-3839::PROPAMIDINE CHLORIDE

SMILES c1cc(ccc1C(=N)N)OCCCOc2ccc(cc2)C(=N)N

InChI Key InChIKey=WTFXJFJYEJZMFO-UHFFFAOYSA-N

Data  2 KI  1 IC50

PDB links: 2 PDB IDs match this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50368092   

TargetTransmembrane protease serine 2(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50368092(GNF-PF-3839 | PROPAMIDINE CHLORIDE)
Affinity DataIC50: 9.00E+3nMAssay Description:Inhibition of TMPRSS2 (247 to 492 residues) (unknown origin) peptidase domain expressed in Escherichia coli BL21 (DE3) incubated for 30 mins followed...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetSerine protease 1(Human)
University of North Carolina

Curated by ChEMBL
LigandPNGBDBM50368092(GNF-PF-3839 | PROPAMIDINE CHLORIDE)
Affinity DataKi:  3.30E+3nMAssay Description:Inhibition of trypsin by amidase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2012
Entry Details Article
PubMed
TargetAcrosin(Pig)
TBA

Curated by ChEMBL
LigandPNGBDBM50368092(GNF-PF-3839 | PROPAMIDINE CHLORIDE)
Affinity DataKi:  3.50E+3nMAssay Description:Reversible competitive inhibition of boar spermatozoa acrosin using BzArgOEt as substrate by Dixon plot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2015
Entry Details Article
PubMed