BDBM50354361 CHEMBL575039::GNF-PF-2787

SMILES CSc1nc(N)c2c3CCCCc3sc2n1

InChI Key InChIKey=NJKBQFTUKUHCGH-UHFFFAOYSA-N

Data  2 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50354361   

TargetLIM domain kinase 1(Human)
The Walter and Eliza Hall Institute of Medical Research

Curated by ChEMBL
LigandPNGBDBM50354361(GNF-PF-2787 | CHEMBL575039)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of LIMK1 using cofilin-2 as substrate after 60 mins by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2012
Entry Details Article
PubMed
TargetLIM domain kinase 1(Human)
The Walter and Eliza Hall Institute of Medical Research

Curated by ChEMBL
LigandPNGBDBM50354361(GNF-PF-2787 | CHEMBL575039)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of LIMK1 using cofilin-2 as substrate after 60 mins by Kinase-Glo assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2012
Entry Details Article
PubMed
TargetATP-dependent translocase ABCB1(Human)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50354361(GNF-PF-2787 | CHEMBL575039)
Affinity DataEC50:  2.65E+3nMAssay Description:Modulation of P-gp overexpressed in human A2780 cells assessed as daunorubicin accumulation preincubated 15 mins prior to daunorubicin addition measu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2020
Entry Details Article
PubMed