BDBM50016461 (S)-2-{4-[2-(2,4-Diamino-pteridin-6-yl)-ethyl]-benzoylamino}-pentanedioic acid::CHEMBL293263::GNF-PF-173

SMILES Nc1nc(N)c2nc(CCc3ccc(cc3)C(=O)N[C@@H](CCC(O)=O)C(O)=O)cnc2n1

InChI Key InChIKey=LGFLRHWJJKLPCC-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50016461   

TargetDihydrofolate reductase(Lactobacillus casei)
University of South Alabama

Curated by ChEMBL
LigandPNGBDBM50016461(CHEMBL293263 | GNF-PF-173 | (S)-2-{4-[2-(2,4-Diami...)
Affinity DataIC50: 20nMAssay Description:Inhibitory activity against dihydrofolate reductase in Lactobacillus casei was determined (glutamate residue 4)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Lactobacillus casei)
University of South Alabama

Curated by ChEMBL
LigandPNGBDBM50016461(CHEMBL293263 | GNF-PF-173 | (S)-2-{4-[2-(2,4-Diami...)
Affinity DataIC50: 20nMAssay Description:Inhibitory activity against dihydrofolate reductase in Lactobacillus casei was determined (glutamate residue 4)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Lactobacillus casei)
University of South Alabama

Curated by ChEMBL
LigandPNGBDBM50016461(CHEMBL293263 | GNF-PF-173 | (S)-2-{4-[2-(2,4-Diami...)
Affinity DataIC50: 22nMAssay Description:Inhibitory activity against dihydrofolate reductase in Lactobacillus casei was determined (glutamate residue 3)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Lactobacillus casei)
University of South Alabama

Curated by ChEMBL
LigandPNGBDBM50016461(CHEMBL293263 | GNF-PF-173 | (S)-2-{4-[2-(2,4-Diami...)
Affinity DataIC50: 18nMAssay Description:Inhibitory activity against dihydrofolate reductase in Lactobacillus casei was determined (glutamate residue 2)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Lactobacillus casei)
University of South Alabama

Curated by ChEMBL
LigandPNGBDBM50016461(CHEMBL293263 | GNF-PF-173 | (S)-2-{4-[2-(2,4-Diami...)
Affinity DataIC50: 34nMAssay Description:Inhibitory activity against dihydrofolate reductase in Lactobacillus casei was determined (glutamate residue 6)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Lactobacillus casei)
University of South Alabama

Curated by ChEMBL
LigandPNGBDBM50016461(CHEMBL293263 | GNF-PF-173 | (S)-2-{4-[2-(2,4-Diami...)
Affinity DataIC50: 21nMAssay Description:Inhibitory activity against dihydrofolate reductase in Lactobacillus casei was determined (glutamate residue 5)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed