BDBM234334 GM6001

SMILES CNC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](CC(C)C)CC(=O)NO

InChI Key InChIKey=NITYDPDXAAFEIT-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 234334   

TargetDisintegrin and metalloproteinase domain-containing protein 17(Human)
Huazhong University of Science and Technology

LigandPNGBDBM234334(GM6001)
Affinity DataIC50: 317nMpH: 9.0 T: 2°CAssay Description:The TACE assay was carried out in 25 mM Tris-HCl buffer (pH 9, 2.5 μM ZnCl2 and 0.005% Brij-35). Then, 15ng TACE was added to buffer solution co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2017
Entry Details Article
PubMed
TargetMatrix metalloproteinase-9(Human)
Huazhong University of Science and Technology

LigandPNGBDBM234334(GM6001)
Affinity DataIC50: 0.260nMpH: 7.5 T: 2°CAssay Description:The MMP-9 assay was performed in 50 mM Tris-HCl buffer (pH 7.5, 10mM CaCl2, 150mM NaCl, 0.05% Brij-35). Then, 30ng Active MMP-9 was added to 50 μ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2017
Entry Details Article
PubMed