BDBM50048201 CHEMBL147580::Flosulide::N-[6-(2,4-Difluoro-phenoxy)-1-oxo-indan-5-yl]-methanesulfonamide

SMILES CS(=O)(=O)Nc1cc2CCC(=O)c2cc1Oc1ccc(F)cc1F

InChI Key InChIKey=CXJONBHNIJFARE-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50048201   

TargetProstaglandin G/H synthase 2(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50048201(N-[6-(2,4-Difluoro-phenoxy)-1-oxo-indan-5-yl]-meth...)
Affinity DataIC50: 21nMAssay Description:In vitro inhibition of prostaglandin G/H synthase 2 expressed in human osteosarcoma 143 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50048201(N-[6-(2,4-Difluoro-phenoxy)-1-oxo-indan-5-yl]-meth...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of Prostaglandin G/H synthase 1 in human U937 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed