BDBM50191588 (2R,3S,6S,7R,8R)-3-[(3-formamido-2-hydroxybenzoyl)amino]-8-hexyl-2,6-dimethyl-4,9-dioxo-1,5-dioxonan-7-yl 3-methylbutanoate::Antimycin A1::Antipiricullin::CHEMBL211501::Fintrol::Virosin::antimycin A::antimycin A1b

SMILES CCCCCC[C@@H]1[C@H]([C@@H](OC(=O)[C@H]([C@H](OC1=O)C)NC(=O)c2cccc(c2O)NC=O)C)OC(=O)CC(C)C

InChI Key InChIKey=UIFFUZWRFRDZJC-UHFFFAOYSA-N

Data  2 KI  8 IC50

PDB links: 6 PDB IDs match this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 50191588   

TargetDihydroorotate dehydrogenase (quinone), mitochondrial(malaria parasite P. falciparum)
Harvard School of Public Health

Curated by ChEMBL
LigandPNGBDBM50191588(Antipiricullin | Fintrol | Antimycin A1 | antimyci...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of Plasmodium falciparum DHODMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2012
Entry Details Article
PubMed
TargetDihydroorotate dehydrogenase (fumarate)(Baker's yeast)
Harvard School of Public Health

Curated by ChEMBL
LigandPNGBDBM50191588(Antipiricullin | Fintrol | Antimycin A1 | antimyci...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of Saccharomyces cerevisiae DHODMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2012
Entry Details Article
PubMed
TargetSuccinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial(Speckled leaf blotch fungus)
Fmc Stine Research Center

Curated by ChEMBL
LigandPNGBDBM50191588(Antipiricullin | Fintrol | Antimycin A1 | antimyci...)
Affinity DataIC50: 2nMAssay Description:Inhibition of Septoria nodorum succinate dehydrogenase and Qi site of mitochondrial respiratory chain complex 3 by FMET2-3 assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2013
Entry Details Article
PubMed
TargetSuccinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial(Speckled leaf blotch fungus)
Fmc Stine Research Center

Curated by ChEMBL
LigandPNGBDBM50191588(Antipiricullin | Fintrol | Antimycin A1 | antimyci...)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of Septoria nodorum succinate dehydrogenase by FMET2 assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2013
Entry Details Article
PubMed
TargetBile salt export pump(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50191588(Antipiricullin | Fintrol | Antimycin A1 | antimyci...)
Affinity DataIC50: 4.50E+4nMAssay Description:Inhibition of human BSEP expressed in fall armyworm sf9 cell plasma membrane vesicles assessed as reduction in vesicle-associated [3H]-taurocholate t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2019
Entry Details Article
PubMed
LigandPNGBDBM50191588(Antipiricullin | Fintrol | Antimycin A1 | antimyci...)
Affinity DataIC50: 1.33E+5nMAssay Description:Inhibition of human MRP4 overexpressed in Sf9 cell membrane vesicles assessed as uptake of [3H]-estradiol-17beta-D-glucuronide in presence of ATP and...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/3/2019
Entry Details Article
PubMed
LigandPNGBDBM50191588(Antipiricullin | Fintrol | Antimycin A1 | antimyci...)
Affinity DataIC50: 1.33E+5nMAssay Description:Inhibition of human MRP3 overexpressed in Sf9 insect cell membrane vesicles assessed as uptake of [3H]-estradiol-17beta-D-glucuronide in presence of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/3/2019
Entry Details Article
PubMed
TargetBile salt export pump(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50191588(Antipiricullin | Fintrol | Antimycin A1 | antimyci...)
Affinity DataIC50: 5.96E+4nMAssay Description:Inhibition of human BSEP overexpressed in Sf9 cell membrane vesicles assessed as uptake of [3H]-taurocholate in presence of ATP measured after 15 to ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/3/2019
Entry Details Article
PubMed
LigandPNGBDBM50191588(Antipiricullin | Fintrol | Antimycin A1 | antimyci...)
Affinity DataKi:  3.82E+3nMAssay Description:Ki values for sodium fluorescein (10 uM) uptake in OATP1B1-transfected CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
LigandPNGBDBM50191588(Antipiricullin | Fintrol | Antimycin A1 | antimyci...)
Affinity DataKi:  3.82E+3nMAssay Description:Ki values for sodium fluorescein (10 uM) uptake in OATP1B3-transfected CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed