BDBM50107843 (-)-FTC::524W91::BW-524W91::CHEBI:31536::Emtricitabine::Emtriva::FTC::FTC-(-)

SMILES C1[C@H](O[C@H](S1)CO)N2C=C(C(=NC2=O)N)F

InChI Key InChIKey=XQSPYNMVSIKCOC-UHFFFAOYSA-N

Data  4 IC50  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50107843   

TargetAlbumin(Human)
Mercer University

Curated by ChEMBL
LigandPNGBDBM50107843(CHEBI:31536 | (-)-FTC | 524W91 | BW-524W91 | Emtri...)
Affinity DataKd:  4.40E+4nMAssay Description:Binding affinity to human serum albumin with excitation at 280 nm after 2 hrs by spectrofluorimetric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2016
Entry Details Article
PubMed
LigandPNGBDBM50107843(CHEBI:31536 | (-)-FTC | 524W91 | BW-524W91 | Emtri...)
Affinity DataIC50: 1.33E+5nMAssay Description:Inhibition of human MRP4 overexpressed in Sf9 cell membrane vesicles assessed as uptake of [3H]-estradiol-17beta-D-glucuronide in presence of ATP and...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/3/2019
Entry Details Article
PubMed
TargetBile salt export pump(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50107843(CHEBI:31536 | (-)-FTC | 524W91 | BW-524W91 | Emtri...)
Affinity DataIC50: 1.33E+5nMAssay Description:Inhibition of human BSEP overexpressed in Sf9 cell membrane vesicles assessed as uptake of [3H]-taurocholate in presence of ATP measured after 15 to ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/3/2019
Entry Details Article
PubMed
LigandPNGBDBM50107843(CHEBI:31536 | (-)-FTC | 524W91 | BW-524W91 | Emtri...)
Affinity DataIC50: 1.33E+5nMAssay Description:Inhibition of human MRP2 overexpressed in Sf9 cell membrane vesicles assessed as uptake of [3H]-estradiol-17beta-D-glucuronide in presence of ATP and...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/3/2019
Entry Details Article
PubMed
LigandPNGBDBM50107843(CHEBI:31536 | (-)-FTC | 524W91 | BW-524W91 | Emtri...)
Affinity DataIC50: 1.33E+5nMAssay Description:Inhibition of human MRP3 overexpressed in Sf9 insect cell membrane vesicles assessed as uptake of [3H]-estradiol-17beta-D-glucuronide in presence of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/3/2019
Entry Details Article
PubMed