BDBM50376403 FR-122047

SMILES COc1ccc(cc1)-c1nc(sc1-c1ccc(OC)cc1)C(=O)N1CCN(C)CC1

InChI Key InChIKey=UBHKJRYGKOSQDJ-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50376403   

TargetProstaglandin G/H synthase 1(Human)
Okayama University Graduate School of Medicine

Curated by ChEMBL
LigandPNGBDBM50376403(FR-122047)
Affinity DataIC50: 28nMAssay Description:Inhibition of COX1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Okayama University Graduate School of Medicine

Curated by ChEMBL
LigandPNGBDBM50376403(FR-122047)
Affinity DataIC50: 6.50E+4nMAssay Description:Inhibition of COX2More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
Okayama University Graduate School of Medicine

Curated by ChEMBL
LigandPNGBDBM50376403(FR-122047)
Affinity DataIC50: 90nMAssay Description:Inhibition of COX1 in human platelet microsomes assessed as reduction in formation of oxidized TMPD using arachidonic acid as substrate preincubated ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Sheep)
University of Bari "Aldo Moro"

Curated by ChEMBL
LigandPNGBDBM50376403(FR-122047)
Affinity DataIC50: 28nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetProstaglandin G/H synthase 2(Human)
Okayama University Graduate School of Medicine

Curated by ChEMBL
LigandPNGBDBM50376403(FR-122047)
Affinity DataIC50: 6.50E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed