BDBM50110690 CHEMBL17377::FOSTRIECIN::Phosphoric acid mono-{3,10-dihydroxy-1-[1-hydroxy-1-methyl-3-(6-oxo-3,6-dihydro-2H-pyran-2-yl)-allyl]-deca-4,6,8-trienyl} ester

SMILES C[C@@](O)(\C=C\[C@H]1CC=CC(=O)O1)[C@@H](C[C@@H](O)\C=C/C=C\C=C\CO)OP(O)(O)=O

InChI Key InChIKey=ZMQRJWIYMXZORG-UHFFFAOYSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50110690   

TargetDNA topoisomerase 2(Fruit fly)
The University of Newcastle

Curated by ChEMBL
LigandPNGBDBM50110690(CHEMBL17377 | Phosphoric acid mono-{3,10-dihydroxy...)
Affinity DataIC50: 4.00E+4nMAssay Description:Inhibition of topoisomerase IIin vitro through a novel, non-DNA-strandcleaving mechanismMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/1/2012
Entry Details Article
PubMed
TargetSerine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B(Chicken)
The University of Newcastle

Curated by ChEMBL
LigandPNGBDBM50110690(CHEMBL17377 | Phosphoric acid mono-{3,10-dihydroxy...)
Affinity DataIC50: 3.40nMAssay Description:Inhibitory activity against partially purified (chicken skeletal muscle) Protein phosphatase 2AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/1/2012
Entry Details Article
PubMed
TargetSerine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B(Chicken)
The University of Newcastle

Curated by ChEMBL
LigandPNGBDBM50110690(CHEMBL17377 | Phosphoric acid mono-{3,10-dihydroxy...)
Affinity DataIC50: 3.40nMAssay Description:Exogenous inhibition concentration of Serine/threonine protein phosphatase 2A (PP2A)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/27/2012
Entry Details Article
PubMed
TargetSerine/threonine-protein phosphatase 4 catalytic subunit(Homo sapiens)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50110690(CHEMBL17377 | Phosphoric acid mono-{3,10-dihydroxy...)
Affinity DataIC50: 3nMAssay Description:Inhibition of PP4 (unknown origin) phosphatase domainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetSerine/threonine-protein phosphatase 5(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50110690(CHEMBL17377 | Phosphoric acid mono-{3,10-dihydroxy...)
Affinity DataIC50: 1nMAssay Description:Inhibition of PPP5C (unknown origin) phosphatase domainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetSerine/threonine-protein phosphatase with EF-hands 1(Homo sapiens)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50110690(CHEMBL17377 | Phosphoric acid mono-{3,10-dihydroxy...)
Affinity DataIC50: 1nMAssay Description:Inhibition of PP7 (unknown origin) phosphatase domainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetSerine/threonine-protein phosphatase 5(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50110690(CHEMBL17377 | Phosphoric acid mono-{3,10-dihydroxy...)
Affinity DataIC50: 1nMAssay Description:Inhibition of PP5 (unknown origin) using [3H]-phosphohistone as substrate by liquid scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed