BDBM50136166 (3R)-N-methyl-3-phenyl-3-[4-(trifluoromethyl)phenoxy]propan-1-amine::(R)-fluoxetine::CHEMBL153036::FLUOXETINE::Methyl-[(R)-3-phenyl-3-(4-trifluoromethyl-phenoxy)-propyl]-amine::Methyl-[3-phenyl-3-(4-trifluoromethyl-phenoxy)-propyl]-amine

SMILES CNCC[C@@H](Oc1ccc(cc1)C(F)(F)F)c1ccccc1

InChI Key InChIKey=RTHCYVBBDHJXIQ-UHFFFAOYSA-N

Data  7 KI  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 11 hits for monomerid = 50136166   

TargetSodium-dependent dopamine transporter(Rat)
Faes Farma

Curated by ChEMBL
LigandPNGBDBM50136166((3R)-N-methyl-3-phenyl-3-[4-(trifluoromethyl)pheno...)
Affinity DataIC50: 1.00E+3nMAssay Description:Binding affinity against dopamine transporter (DAT) by displacement of [3H]WIN-35428 in male wistar ratsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetTransporter(Rat)
Faes Farma

Curated by ChEMBL
LigandPNGBDBM50136166((3R)-N-methyl-3-phenyl-3-[4-(trifluoromethyl)pheno...)
Affinity DataIC50: 1.00E+3nMAssay Description:Binding affinity against norepinephrine transporter (NET) by displacement of [3H]nisoxetine in male wistar ratsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Rat)
Faes Farma

Curated by ChEMBL
LigandPNGBDBM50136166((3R)-N-methyl-3-phenyl-3-[4-(trifluoromethyl)pheno...)
Affinity DataIC50: 1.00E+3nMAssay Description:Binding affinity against 5-hydroxytryptamine 2A receptor by displacement of [3H]-ketanserin from rat prefrontal cerebral cortex mambranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
Faes Farma

Curated by ChEMBL
LigandPNGBDBM50136166((3R)-N-methyl-3-phenyl-3-[4-(trifluoromethyl)pheno...)
Affinity DataIC50: 1.00E+3nMAssay Description:Binding affinity against 5-hydroxytryptamine 1A receptor (5-HT1A) by displacement of [3H]8-OH-DPAT from rat hippocampus membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Rat)
Faes Farma

Curated by ChEMBL
LigandPNGBDBM50136166((3R)-N-methyl-3-phenyl-3-[4-(trifluoromethyl)pheno...)
Affinity DataKi:  30.8nMAssay Description:Binding affinity to the serotonin transporter (SERT) measured by displacement of [3H]paroxetine in male wistar ratsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Rat)
Faes Farma

Curated by ChEMBL
LigandPNGBDBM50136166((3R)-N-methyl-3-phenyl-3-[4-(trifluoromethyl)pheno...)
Affinity DataKi:  1.66E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2011
Entry Details
PubMed
LigandPNGBDBM50136166((3R)-N-methyl-3-phenyl-3-[4-(trifluoromethyl)pheno...)
Affinity DataKi:  3.39E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2011
Entry Details
PubMed
TargetBeta-arrestin-2(Bovine)
Eli Lilly

Curated by PDSP Ki Database
LigandPNGBDBM50136166((3R)-N-methyl-3-phenyl-3-[4-(trifluoromethyl)pheno...)
Affinity DataKi:  3.63E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2011
Entry Details
PubMed
Target5-hydroxytryptamine 1D receptor(Bovine)
Eli Lilly

Curated by PDSP Ki Database
LigandPNGBDBM50136166((3R)-N-methyl-3-phenyl-3-[4-(trifluoromethyl)pheno...)
Affinity DataKi:  3.89E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2011
Entry Details
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
Faes Farma

Curated by ChEMBL
LigandPNGBDBM50136166((3R)-N-methyl-3-phenyl-3-[4-(trifluoromethyl)pheno...)
Affinity DataKi:  5.89E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2011
Entry Details
PubMed
LigandPNGBDBM50136166((3R)-N-methyl-3-phenyl-3-[4-(trifluoromethyl)pheno...)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2011
Entry Details
PubMed