BDBM50030178 (R)-4-Hydroxy-1-(1-methyl-1H-indole-3-carbonyl)-pyrrolidine-2-carboxylic acid [(R)-1-(benzyl-methyl-carbamoyl)-2-naphthalen-2-yl-ethyl]-amide::CHEMBL303548::FK 888

SMILES CN(Cc1ccccc1)C(=O)[C@@H](Cc1ccc2ccccc2c1)NC(=O)C1C[C@@H](O)CN1C(=O)c1cn(C)c2ccccc12

InChI Key InChIKey=BFNKQTIJVFGCKQ-UHFFFAOYSA-N

Data  5 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50030178   

TargetSubstance-P receptor(Guinea pig)
Fujisawa Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50030178(FK 888 | CHEMBL303548 | (R)-4-Hydroxy-1-(1-methyl-...)
Affinity DataIC50: 1.70nMAssay Description:In vitro binding affinity against substance P receptor using [3H]SP as radioligand in guinea pig lung membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2012
Entry Details Article
PubMed
TargetSubstance-P receptor(Human)
Hoechst Marion Roussel

Curated by PDSP Ki Database
LigandPNGBDBM50030178(FK 888 | CHEMBL303548 | (R)-4-Hydroxy-1-(1-methyl-...)
Affinity DataKi:  1.49nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2012
Entry Details
PubMed
TargetSubstance-P receptor(Guinea pig)
Fujisawa Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50030178(FK 888 | CHEMBL303548 | (R)-4-Hydroxy-1-(1-methyl-...)
Affinity DataKi:  3.13nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2012
Entry Details
PubMed
TargetSubstance-K receptor(Human)
Hoechst Marion Roussel

Curated by PDSP Ki Database
LigandPNGBDBM50030178(FK 888 | CHEMBL303548 | (R)-4-Hydroxy-1-(1-methyl-...)
Affinity DataKi:  1.52E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2012
Entry Details
PubMed
TargetSubstance-P receptor(Rat)
Hoechst Marion Roussel

Curated by PDSP Ki Database
LigandPNGBDBM50030178(FK 888 | CHEMBL303548 | (R)-4-Hydroxy-1-(1-methyl-...)
Affinity DataKi:  2.07E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2012
Entry Details
PubMed
TargetNeuromedin-K receptor(Guinea pig)
Hoechst Marion Roussel

Curated by PDSP Ki Database
LigandPNGBDBM50030178(FK 888 | CHEMBL303548 | (R)-4-Hydroxy-1-(1-methyl-...)
Affinity DataKi:  5.62E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2012
Entry Details
PubMed