BDBM50135167 (+)-epicatechin::(-) epicatechine::(2S,3S)-2-(3,4-Dihydroxy-phenyl)-chroman-3,5,7-triol::CHEMBL129482::Epicatechin

SMILES O[C@H]1Cc2c(O)cc(O)cc2O[C@H]1c1ccc(O)c(O)c1

InChI Key InChIKey=PFTAWBLQPZVEMU-UHFFFAOYSA-N

Data  8 IC50  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50135167   

TargetProstaglandin G/H synthase 1(Sheep)
University of Pennsylvania School of Medicine

Curated by ChEMBL
LigandPNGBDBM50135167(Epicatechin | (-) epicatechine | (2S,3S)-2-(3,4-Di...)
Affinity DataIC50: 1.28E+4nMAssay Description:Inhibition of cyclooxygenase activity of COX1 in sheep seminal vesicle in presence of 1 mM phenol by cyclooxygenase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2012
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Sheep)
University of Pennsylvania School of Medicine

Curated by ChEMBL
LigandPNGBDBM50135167(Epicatechin | (-) epicatechine | (2S,3S)-2-(3,4-Di...)
Affinity DataKd:  2.51E+4nMAssay Description:Binding affinity to COX1 in sheep seminal vesicleMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2012
Entry Details Article
PubMed
TargetFatty acid synthase(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50135167(Epicatechin | (-) epicatechine | (2S,3S)-2-(3,4-Di...)
Affinity DataIC50: 1.00E+6nMAssay Description:Inhibition of FAS at 1000 uMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2011
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Kyungpook National University

Curated by ChEMBL
LigandPNGBDBM50135167(Epicatechin | (-) epicatechine | (2S,3S)-2-(3,4-Di...)
Affinity DataIC50: 2.80E+4nMAssay Description:Inhibition of human Beta-secretase 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Kyungpook National University

Curated by ChEMBL
LigandPNGBDBM50135167(Epicatechin | (-) epicatechine | (2S,3S)-2-(3,4-Di...)
Affinity DataIC50: 2.80E+4nMAssay Description:Inhibition of human Beta-secretase 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Sheep)
University of Pennsylvania School of Medicine

Curated by ChEMBL
LigandPNGBDBM50135167(Epicatechin | (-) epicatechine | (2S,3S)-2-(3,4-Di...)
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibition of peroxidase activity of COX1 in heep seminal vesicle by TMPD assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2012
Entry Details Article
PubMed
TargetNeuraminidase(Influenza A virus)
Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM50135167(Epicatechin | (-) epicatechine | (2S,3S)-2-(3,4-Di...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of Influenza A Jinan/15/90 H3N2 virus neuraminidase activity by MUN-ANA substrate based fluorimetric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2020
Entry Details Article
PubMed
TargetNeuraminidase(Influenza A virus)
Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM50135167(Epicatechin | (-) epicatechine | (2S,3S)-2-(3,4-Di...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of Influenza A PR/8/34 H1N1 virus neuraminidase activity by MUN-ANA substrate based fluorimetric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2020
Entry Details Article
PubMed
TargetNeuraminidase(Influenza A virus)
Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM50135167(Epicatechin | (-) epicatechine | (2S,3S)-2-(3,4-Di...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of Influenza A Jiangsu/10/2003 virus neuraminidase activity by MUN-ANA substrate based fluorimetric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2020
Entry Details Article
PubMed