BDBM50328731 CHEMBL1269025::Edoxaban

SMILES CN(C)C(=O)[C@H]1CC[C@H](NC(=O)C(=O)Nc2ccc(Cl)cn2)[C@@H](C1)NC(=O)c1nc2CCN(C)Cc2s1

InChI Key InChIKey=HGVDHZBSSITLCT-UHFFFAOYSA-N

Data  4 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50328731   

TargetCoagulation factor X(Human)
Guangdong-Macau Traditional Chinese Medicine Technology Industrial Park Development

Curated by ChEMBL
LigandPNGBDBM50328731(Edoxaban | CHEMBL1269025)
Affinity DataIC50: 3.40nMAssay Description:Inhibition of human coagulation factor 10a using Z-D-Arg-Gly-Arg-pNA.2HCl as substrate preincubated for 15 mins followed by substrate addition by UV ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Guangdong-Macau Traditional Chinese Medicine Technology Industrial Park Development

Curated by ChEMBL
LigandPNGBDBM50328731(Edoxaban | CHEMBL1269025)
Affinity DataIC50: 3.40nMAssay Description:Inhibition of human factor Xa using Z-D-Arg-Gly-Arg-pNA.2HCl as substrate preincubated for 15 mins followed by substrate addition by UV absorption an...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Guangdong-Macau Traditional Chinese Medicine Technology Industrial Park Development

Curated by ChEMBL
LigandPNGBDBM50328731(Edoxaban | CHEMBL1269025)
Affinity DataKi:  0.560nMAssay Description:Inhibition of factor 10aMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/2/2013
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Guangdong-Macau Traditional Chinese Medicine Technology Industrial Park Development

Curated by ChEMBL
LigandPNGBDBM50328731(Edoxaban | CHEMBL1269025)
Affinity DataKi:  0.561nMAssay Description:Inhibition of factor Xa (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
TargetCoagulation factor X(Human)
Guangdong-Macau Traditional Chinese Medicine Technology Industrial Park Development

Curated by ChEMBL
LigandPNGBDBM50328731(Edoxaban | CHEMBL1269025)
Affinity DataKi:  0.561nMAssay Description:Inhibition of activated human factor XMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50328731(Edoxaban | CHEMBL1269025)
Affinity DataKi:  3nMAssay Description:Inhibition of activated human factor X/activated human factor V complex derived prothrombinase using S-2238 as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed