BDBM391600 ETI-T-255::US10300048, Compound 2::US10300048, ETI-T-255

SMILES CCOc1cc(\C=C2/S\C(=N/c3ccc(F)cc3)N(C2=O)c2ccc(F)cc2)ccc1O

InChI Key InChIKey=LWHKWPLBZPXOSW-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 391600   

TargetFatty-acid amide hydrolase 1(Human)
Universitat Bern

US Patent
LigandPNGBDBM391600(US10300048, Compound 2 | US10300048, ETI-T-255 | E...)
Affinity DataIC50: 74nMAssay Description:Screening for AEA cellular uptake inhibition was performed in a semi-automated procedure: Pipetting and washing steps were performed by a Biomek3000 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2020
Entry Details
Go to US Patent

TargetFatty-acid amide hydrolase 1(Human)
Universitat Bern

US Patent
LigandPNGBDBM391600(US10300048, Compound 2 | US10300048, ETI-T-255 | E...)
Affinity DataIC50: 5.62E+4nMAssay Description:Hydrolysis of [3H]-AEA by FAAH was determined as previously described in cell homogenates of U937 cells (0.18 mg protein) (Omeir et al., 1999, Bioche...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2020
Entry Details
Go to US Patent

TargetFatty-acid amide hydrolase 1(Human)
Universitat Bern

US Patent
LigandPNGBDBM391600(US10300048, Compound 2 | US10300048, ETI-T-255 | E...)
Affinity DataIC50: 74nMAssay Description:Screening for AEA cellular uptake inhibition was performed in a semi-automated procedure: Pipetting and washing steps were performed by a Biomek3000 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2020
Entry Details
Go to US Patent

TargetFatty-acid amide hydrolase 1(Human)
Universitat Bern

US Patent
LigandPNGBDBM391600(US10300048, Compound 2 | US10300048, ETI-T-255 | E...)
Affinity DataIC50: 5.62E+4nMAssay Description:Hydrolysis of [3H]-AEA by FAAH was determined as previously described in cell homogenates of U937 cells (0.18 mg protein) (Omeir et al., 1999, Bioche...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2020
Entry Details
Go to US Patent