BDBM391622 ETI-T-209::US10300048, Compound 23

SMILES Oc1c(Cl)cc(\C=C2\S\C(=N/c3ccccc3)N(Cc3ccco3)C2=O)cc1Cl

InChI Key InChIKey=VPMSMQTXADUFCU-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 391622   

TargetFatty-acid amide hydrolase 1(Human)
Universitat Bern

US Patent
LigandPNGBDBM391622(US10300048, Compound 23 | ETI-T-209)
Affinity DataIC50: 990nMAssay Description:Screening for AEA cellular uptake inhibition was performed in a semi-automated procedure: Pipetting and washing steps were performed by a Biomek3000 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2020
Entry Details
Go to US Patent

TargetFatty-acid amide hydrolase 1(Human)
Universitat Bern

US Patent
LigandPNGBDBM391622(US10300048, Compound 23 | ETI-T-209)
Affinity DataIC50: 6.03E+4nMAssay Description:Hydrolysis of [3H]-AEA by FAAH was determined as previously described in cell homogenates of U937 cells (0.18 mg protein) (Omeir et al., 1999, Bioche...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2020
Entry Details
Go to US Patent