BDBM50425019 CHEMBL2312201::EN300-99795

SMILES Nc1ccc([N+]([O-])=O)c2ccccc12

InChI Key InChIKey=BVPJPRYNQHAOPQ-UHFFFAOYSA-N

Data  3 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50425019   

TargetReplicase polyprotein 1ab(2019-nCoV)
Cornell University

LigandPNGBDBM50425019(CHEMBL2312201 | EN300-99795)
Affinity DataIC50: 2.14E+3nMAssay Description:IC50 values were determined for the whole plate in case of Chan-Lam coupling, using 5 point 3-fold dilutions (starting from 10 μM).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/27/2023
Entry Details
PubMed
TargetCathepsin B(Human)
University of Ljubljana

Curated by ChEMBL
LigandPNGBDBM50425019(CHEMBL2312201 | EN300-99795)
Affinity DataKi:  1.11E+5nMAssay Description:Mixed inhibition of human recombinant cathepsin B endopeptidase activity using Z-Arg-Arg-AMC substrate assessed as inhibition constant for enzyme-sub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetCathepsin B(Human)
University of Ljubljana

Curated by ChEMBL
LigandPNGBDBM50425019(CHEMBL2312201 | EN300-99795)
Affinity DataKi:  1.47E+5nMAssay Description:Noncompetitive inhibition of human recombinant cathepsin B exopeptidase activity using Abz-Gly-Ile-Val-Arg-Ala-Lys(Dnp)-OH substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetCathepsin B(Human)
University of Ljubljana

Curated by ChEMBL
LigandPNGBDBM50425019(CHEMBL2312201 | EN300-99795)
Affinity DataKi:  2.17E+5nMAssay Description:Mixed inhibition of human recombinant cathepsin B endopeptidase activity using Z-Arg-Arg-AMC substrate assessed as inhibition constant for enzyme-inh...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed