BDBM50097721 CHEMBL1879790::EN300-11843

SMILES CN1CCN(CC1)c2ccccc2N

InChI Key InChIKey=INWHDRNGZMHXEZ-UHFFFAOYSA-N

Data  1 KI  3 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50097721   

TargetReplicase polyprotein 1ab(2019-nCoV)
Cornell University

LigandPNGBDBM50097721(CHEMBL1879790 | EN300-11843)
Affinity DataIC50: 2.09E+3nMAssay Description:IC50 values were determined for the whole plate in case of Chan-Lam coupling, using 5 point 3-fold dilutions (starting from 10 μM).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/27/2023
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Cornell University

LigandPNGBDBM50097721(CHEMBL1879790 | EN300-11843)
Affinity DataIC50: 2nMAssay Description:IC50 values were determined using 12 point 2-fold dilutions (starting from 10 μM).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/27/2023
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Cornell University

LigandPNGBDBM50097721(CHEMBL1879790 | EN300-11843)
Affinity DataIC50: 1.80nMAssay Description:Inhibition of SARS-Cov-2 main protease using fluorogenic substrate [5-FAM]-AVLQSGFR-[Lys(Dabcyl)]-K-amide by fluorogenic assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetAlpha-2C adrenergic receptor(Human)
Gedeon Richter Plc., Gy�Mroi�T 19-21, Budapest H-1103, Hungary.

Curated by ChEMBL
LigandPNGBDBM50097721(CHEMBL1879790 | EN300-11843)
Affinity DataKi:  240nMAssay Description:Displacement of [3H]-UK14304 from recombinant human alpha2c adrenergic receptor expressed in CHOK1 cell membranes after 30 mins by scintillation coun...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2016
Entry Details Article
PubMed