BDBM50185775 7-(1-(2,4-difluorophenethyl)piperazine-4-carbonyl)-1H-indole-3-carbonitrile::CHEMBL207566::EMD-281014

SMILES Fc1ccc(CCN2CCN(CC2)C(=O)c2cccc3c(c[nH]c23)C#N)c(F)c1

InChI Key InChIKey=ZRXBCXGGXCXHCB-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50185775   

Target5-hydroxytryptamine receptor 2A(Human)
Merck Sharp & Dohme

Curated by ChEMBL
LigandPNGBDBM50185775(EMD-281014 | 7-(1-(2,4-difluorophenethyl)piperazin...)
Affinity DataKi:  0.870nMAssay Description:Binding affinity to human 5HT2AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
Merck Sharp & Dohme

Curated by ChEMBL
LigandPNGBDBM50185775(EMD-281014 | 7-(1-(2,4-difluorophenethyl)piperazin...)
Affinity DataKi:  557nMAssay Description:Binding affinity to human 5HT2CMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Merck Sharp & Dohme

Curated by ChEMBL
LigandPNGBDBM50185775(EMD-281014 | 7-(1-(2,4-difluorophenethyl)piperazin...)
Affinity DataKi: >1.00E+3nMAssay Description:Binding affinity to human D2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Merck Sharp & Dohme

Curated by ChEMBL
LigandPNGBDBM50185775(EMD-281014 | 7-(1-(2,4-difluorophenethyl)piperazin...)
Affinity DataKi:  1.27E+3nMAssay Description:Binding affinity to human IKrMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed