BDBM50569838 EDO-S 101::EDO-S-101::EDO-S101::Tinostamustine

SMILES Cn1c(CCCCCCC(=O)NO)nc2cc(ccc12)N(CCCl)CCCl

InChI Key InChIKey=GISXTRIGVCKQBX-UHFFFAOYSA-N

Data  8 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50569838   

TargetHistone deacetylase 1/2/3/8(Human)
Southern Medical University

Curated by ChEMBL
LigandPNGBDBM50569838(Tinostamustine | EDO-S 101 | EDO-S-101 | EDO-S101)
Affinity DataIC50: 6nMAssay Description:Inhibition of HDAC class1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Menoufia University

Curated by ChEMBL
LigandPNGBDBM50569838(Tinostamustine | EDO-S 101 | EDO-S-101 | EDO-S101)
Affinity DataIC50: 10nMAssay Description:Inhibition of HDAC1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
TargetHistone deacetylase 1(Human)
Menoufia University

Curated by ChEMBL
LigandPNGBDBM50569838(Tinostamustine | EDO-S 101 | EDO-S-101 | EDO-S101)
Affinity DataIC50: 17nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetHistone deacetylase 2(Human)
Guru Ghasidas University

Curated by ChEMBL
LigandPNGBDBM50569838(Tinostamustine | EDO-S 101 | EDO-S-101 | EDO-S101)
Affinity DataIC50: 10nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetHistone deacetylase 3(Human)
Guru Ghasidas University

Curated by ChEMBL
LigandPNGBDBM50569838(Tinostamustine | EDO-S 101 | EDO-S-101 | EDO-S101)
Affinity DataIC50: 25nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetHistone deacetylase 4(Human)
Guru Ghasidas University

Curated by ChEMBL
LigandPNGBDBM50569838(Tinostamustine | EDO-S 101 | EDO-S-101 | EDO-S101)
Affinity DataIC50: 6.40nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetHistone deacetylase 5(Human)
Guru Ghasidas University

Curated by ChEMBL
LigandPNGBDBM50569838(Tinostamustine | EDO-S 101 | EDO-S-101 | EDO-S101)
Affinity DataIC50: 107nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetHistone deacetylase 6(Human)
Guru Ghasidas University

Curated by ChEMBL
LigandPNGBDBM50569838(Tinostamustine | EDO-S 101 | EDO-S-101 | EDO-S101)
Affinity DataIC50: 72nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed