BDBM50240047 CHEBI:4724::Dyclonine::US20240358711, Compound Dyclonine

SMILES CCCCOc1ccc(cc1)C(=O)CCN2CCCCC2

InChI Key InChIKey=BZEWSEKUUPWQDQ-UHFFFAOYSA-N

Data  4 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50240047   

TargetBile salt export pump(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50240047(CHEBI:4724 | Dyclonine | US20240358711, Compound D...)
Affinity DataIC50: 2.75E+5nMAssay Description:Inhibition of human BSEP expressed in baculovirus transfected fall armyworm Sf21 cell membranes vesicles assessed as reduction in ATP-dependent [3H]-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2019
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
Prin. K. M. Kundnani College of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50240047(CHEBI:4724 | Dyclonine | US20240358711, Compound D...)
Affinity DataIC50: 181nMAssay Description:Inhibition of AChE (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase ROS(Human)
Immunyx Pharma

US Patent
LigandPNGBDBM50240047(CHEBI:4724 | Dyclonine | US20240358711, Compound D...)
Affinity DataIC50: 2.50E+3nMAssay Description:A high-throughput screen was performed to find molecules that inhibit ROS production by neutrophils. Extracted human neutrophils were purified and ke...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2025
Entry Details
Go to US Patent

TargetProto-oncogene tyrosine-protein kinase ROS(Mouse)
Immunyx Pharma

US Patent
LigandPNGBDBM50240047(CHEBI:4724 | Dyclonine | US20240358711, Compound D...)
Affinity DataIC50: 2.00E+3nMAssay Description:A high-throughput screen was performed to find molecules that inhibit ROS production by neutrophils. Extracted human neutrophils were purified and ke...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2025
Entry Details
Go to US Patent