BDBM39862 Deprenyl::METHYL-(1-METHYL-2-PHENYL-ETHYL)-PROP-2-YNYL-AMINE HYDROCHLORIDE::MLS000069378::N-methyl-1-phenyl-N-prop-2-ynyl-2-propanamine;hydrochloride::N-methyl-1-phenyl-N-prop-2-ynyl-propan-2-amine;hydrochloride::N-methyl-1-phenyl-N-prop-2-ynylpropan-2-amine;hydrochloride::SMR000058408::Selegiline::cid_92913::methyl-(1-methyl-2-phenyl-ethyl)-propargyl-amine;hydrochloride

SMILES CC(Cc1ccccc1)N(C)CC#C

InChI Key InChIKey=MEZLKOACVSPNER-UHFFFAOYSA-N

Data  7 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 39862   

Target14-3-3 protein gamma(Human)
Emory University

Curated by PubChem BioAssay
LigandPNGBDBM39862(Selegiline | MLS000069378 | N-methyl-1-phenyl-N-pr...)
Affinity DataIC50: 5.00E+4nMAssay Description:NIH Molecular Libraries Screening Centers Network [MLSCN] Emory Chemical Biology Discovery Center in MLSCN MLSCN Grant: 1 X01MH78953-01 The 14-3-3 pr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/5/2011
Entry Details
PCBioAssay
TargetIntegrin alpha-4(Human)
Nmmlsc

Curated by PubChem BioAssay
LigandPNGBDBM39862(Selegiline | MLS000069378 | N-methyl-1-phenyl-N-pr...)
Affinity DataEC50:  1.00E+5nMAssay Description:Assay Support: 1 X01 MH077638-01 MLSCN Assay for Allosteric Ligands for the VLA-4 Integrin PI: SKLAR, LARRY A University of New Mexico Assay Overview...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2011
Entry Details
PCBioAssay
TargetAmine oxidase [flavin-containing] A(Human)
Quaid-I-Azam University

LigandPNGBDBM39862(Selegiline | MLS000069378 | N-methyl-1-phenyl-N-pr...)
Affinity DataIC50: 6.73E+4nMpH: 7.4Assay Description:The assay was performed in a polystyrene 96-well plate having flat bottom containing 200 μL of the total reaction mixture. For each assay, mixtu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2017
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] B(Human)
Quaid-I-Azam University

LigandPNGBDBM39862(Selegiline | MLS000069378 | N-methyl-1-phenyl-N-pr...)
Affinity DataIC50: 19.6nMpH: 7.4Assay Description:The assay was performed in a polystyrene 96-well plate having flat bottom containing 200 μL of the total reaction mixture. For each assay, mixtu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2017
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] A(Human)
Quaid-I-Azam University

LigandPNGBDBM39862(Selegiline | MLS000069378 | N-methyl-1-phenyl-N-pr...)
Affinity DataIC50: 6.73E+4nMAssay Description:Inhibition of human recombinant MAO-A expressed in baculovirus infected BTI cells using p-tyramine as substrate after 15 mins by Amplex Red-based flu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2017
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] B(Human)
Quaid-I-Azam University

LigandPNGBDBM39862(Selegiline | MLS000069378 | N-methyl-1-phenyl-N-pr...)
Affinity DataIC50: 19nMAssay Description:Inhibition of human recombinant MAO-B expressed in baculovirus infected BTI cells using p-tyramine as substrate after 15 mins by Amplex Red-based flu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2017
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] A(Rat)
Government College University

Curated by ChEMBL
LigandPNGBDBM39862(Selegiline | MLS000069378 | N-methyl-1-phenyl-N-pr...)
Affinity DataIC50: 6.73E+4nMAssay Description:Inhibition of MAO-A in rat liver mitochondria using p-tyramine as substrate preincubated for 10 mins followed by substrate addition measured after 30...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/8/2020
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] B(Rat)
Government College University

Curated by ChEMBL
LigandPNGBDBM39862(Selegiline | MLS000069378 | N-methyl-1-phenyl-N-pr...)
Affinity DataIC50: 20nMAssay Description:Inhibition of MAO-B in rat liver mitochondria using p-tyramine as substrate preincubated for 10 mins followed by substrate addition measured after 30...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/8/2020
Entry Details Article
PubMed