BDBM50014996 (+/-)2-(2,5-Dimethoxy-4-nitro-phenyl)-1-methyl-ethylamine::(-)2-(2,5-Dimethoxy-4-nitro-phenyl)-1-methyl-ethylamine::2-(2,5-Dimethoxy-4-nitro-phenyl)-1-methyl-ethylamine::2-(2,5-Dimethoxy-4-nitro-phenyl)-1-methyl-ethylamine((R)-(-)-DON)::2-(2,5-Dimethoxy-4-nitro-phenyl)-1-methyl-ethylamine(DON)::CHEMBL8301::DON

SMILES COc1cc(c(OC)cc1CC(C)N)[N+]([O-])=O

InChI Key InChIKey=JQJRESSXOVAECC-UHFFFAOYSA-N

Data  7 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50014996   

TargetAmine oxidase [flavin-containing] A(Rat)
Universidad De Chile

Curated by ChEMBL
LigandPNGBDBM50014996(DON | 2-(2,5-Dimethoxy-4-nitro-phenyl)-1-methyl-et...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibitory concentration against monoamine oxidase A in rat brain mitochondrial suspensionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Eli Lilly

Curated by PDSP Ki Database
LigandPNGBDBM50014996(DON | 2-(2,5-Dimethoxy-4-nitro-phenyl)-1-methyl-et...)
Affinity DataKi:  5.5nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
Eli Lilly

Curated by PDSP Ki Database
LigandPNGBDBM50014996(DON | 2-(2,5-Dimethoxy-4-nitro-phenyl)-1-methyl-et...)
Affinity DataKi:  22.4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2B(Human)
Eli Lilly

Curated by PDSP Ki Database
LigandPNGBDBM50014996(DON | 2-(2,5-Dimethoxy-4-nitro-phenyl)-1-methyl-et...)
Affinity DataKi:  166nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2012
Entry Details Article
PubMed
LigandPNGBDBM50014996(DON | 2-(2,5-Dimethoxy-4-nitro-phenyl)-1-methyl-et...)
Affinity DataKi:  248nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2012
Entry Details Article
PubMed
TargetSerotonin 2 (5-HT2) receptor(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50014996(DON | 2-(2,5-Dimethoxy-4-nitro-phenyl)-1-methyl-et...)
Affinity DataKi:  300nMAssay Description:Binding affinity to rat cortical membranes at 5-hydroxytryptamine 2 (5-HT2) receptor using [3H]KET as a radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2012
Entry Details Article
PubMed
TargetSerotonin 2 (5-HT2) receptor(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50014996(DON | 2-(2,5-Dimethoxy-4-nitro-phenyl)-1-methyl-et...)
Affinity DataKi:  300nMAssay Description:Binding affinity against 5-hydroxytryptamine 2 receptor of rat frontal cortex using [3H]ketanserin radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/21/2019
Entry Details Article
PubMed
LigandPNGBDBM50014996(DON | 2-(2,5-Dimethoxy-4-nitro-phenyl)-1-methyl-et...)
Affinity DataKi:  1.41E+4nMAssay Description:Evaluated for binding affinity towards rat cortical membranes at 5-hydroxytryptamine 1 receptor binding site by using [3H]-5-HT as a radioligand.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2012
Entry Details Article
PubMed