BDBM50121958 4,4'-Biphenyldiol::4,4'-Dihydroxybiphenyl::4,4'-biphenol::4,4'-dioxydiphenyl::CHEMBL76398::DOD::US9688816, 6::[1,1'-biphenyl]-4,4'-diol::biphenyl-4,4'-diol::p,p'-biphenol::p,p'-dihydroxybiphenyl

SMILES c1cc(ccc1c2ccc(cc2)O)O

InChI Key InChIKey=VCCBEIPGXKNHFW-UHFFFAOYSA-N

Data  2 IC50  3 Kd

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50121958   

TargetStromelysin-1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50121958([1,1'-biphenyl]-4,4'-diol | biphenyl-4,4'-diol | 4...)
Affinity DataKd:  1.50E+5nMAssay Description:Binding to stromelysin (MMP-3) in the presence of 1-NapthohydroxamateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetStromelysin-1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50121958([1,1'-biphenyl]-4,4'-diol | biphenyl-4,4'-diol | 4...)
Affinity DataKd:  1.60E+5nMAssay Description:Binding to stromelysin (MMP-3) in the presence of acetohydroxamic acidMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGTP-binding protein Rheb(Human)
Ruhr University of Bochum

Curated by ChEMBL
LigandPNGBDBM50121958([1,1'-biphenyl]-4,4'-diol | biphenyl-4,4'-diol | 4...)
Affinity DataKd:  1.50E+6nMAssay Description:Binding affinity to full-length Rheb (unknown origin) by NMR spectroscopic analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
Sabic Global Technologies

US Patent
LigandPNGBDBM50121958([1,1'-biphenyl]-4,4'-diol | biphenyl-4,4'-diol | 4...)
Affinity DataIC50: 2.50E+5nMAssay Description:Competitive binding assays were performed by incubating rhER alpha (α) and beta 1 (β1) receptors with 10 nM [3H]estradiol (the radio ligand...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2018
Entry Details
Go to US Patent

TargetEstrogen receptor beta(Human)
Sabic Global Technologies

US Patent
LigandPNGBDBM50121958([1,1'-biphenyl]-4,4'-diol | biphenyl-4,4'-diol | 4...)
Affinity DataIC50: 1.70E+3nMAssay Description:Competitive binding assays were performed by incubating rhER alpha (α) and beta 1 (β1) receptors with 10 nM [3H]estradiol (the radio ligand...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2018
Entry Details
Go to US Patent